Answer Posted / jagadeeshchandra
#Base line is nothing but the detectors response to the
mobile phase.(gc,hplc)
#Base line should be stable to start a run.
#Un stabilized base line is called as base line noise.
#Base line noise is of many types..
1)Cyclic base line
2)Synchorinise noise
3)Asynchorinise noise
4)Base line drift
5)Spikes
6)Negative peaks
7)No peaks
#Base line noise is attributed due to mobile phase,sample,
system problems.leaks in the system,temperature variations
in lab etc..
Is This Answer Correct ? | 14 Yes | 1 No |
Post New Answer View All Answers
Why irmoisture balance is used for corrugated box moisture testing
What is column in chromatography?
What is gelatinization?
how the compound separate in coulunm,explain
What is the difference between chromatographic purity and related substances?
what is diffrence between specificity and selecivity?
what is the extinction coefficient for Indomethacin or at 319nm wave length.
we can use expired sample for validation and analyst qualification?
how to calculate elemental impurities?
identification is for unknown? qualification for known? reporting for LOQ?
why does used dry caffien in HPLC calibration?
if content uniformity passing but dissolution varrying then what is next step?
How require to develop GC method? how to select diluent, GAS, column selection and other chromatographic conditions?
how to decide for one product require water content or LOD?
Difference between hlaf and rlaf