What is a base line?

Answer Posted / jagadeeshchandra

#Base line is nothing but the detectors response to the
mobile phase.(gc,hplc)

#Base line should be stable to start a run.

#Un stabilized base line is called as base line noise.

#Base line noise is of many types..
1)Cyclic base line
2)Synchorinise noise
3)Asynchorinise noise
4)Base line drift
5)Spikes
6)Negative peaks
7)No peaks

#Base line noise is attributed due to mobile phase,sample,
system problems.leaks in the system,temperature variations
in lab etc..

Is This Answer Correct ?    14 Yes 1 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

Why irmoisture balance is used for corrugated box moisture testing

1938


What is column in chromatography?

1766


What is gelatinization?

1183


how the compound separate in coulunm,explain

1949


What is the difference between chromatographic purity and related substances?

795






what is diffrence between specificity and selecivity?

320


what is the extinction coefficient for Indomethacin or at 319nm wave length.

3525


we can use expired sample for validation and analyst qualification?

308


how to calculate elemental impurities?

553


identification is for unknown? qualification for known? reporting for LOQ?

292


why does used dry caffien in HPLC calibration?

1573


if content uniformity passing but dissolution varrying then what is next step?

394


How require to develop GC method? how to select diluent, GAS, column selection and other chromatographic conditions?

283


how to decide for one product require water content or LOD?

331


Difference between hlaf and rlaf

1660