perchloric acid&glacal acetic acid both are acids but
reaction is complete in volumetric titrations.how?
Answer Posted / kiranreddy munnangi
Perchloric acid is Very strong acid
Acetic acid is weak acid
In presence of very strong acid like pechloric acid
acetic acid bahaves as a base and accepts a proton(H+) from
perchloric acid and forms CH3COOH<2+
Non aqaous titrations are used to titrate the samples
which are very weak bases or salts of weak bases.So in our
titration we take a weak base sample in a titration vessel.
By taking protons from perchloric acid, acetic acid behaves
like a strong acid in presence of a weak base. So reaction
occurs between strong acid and a weak base.
Role of acetic acid:
1.In presence of strong perchloric acid it behaves like a
base and accepts protons.
2.In presence of weak base it behaves as a strong acid and
donates protons to weak base.Protons transfer from
perchloric acid to weak base through acetic acid.
Perchloric acid-------->acetic acid--------->weak base
Finally it is strong acid weak base titration but not acid
acid titration.
| Is This Answer Correct ? | 19 Yes | 1 No |
Post New Answer View All Answers
What are the primary considerations in extractables and Leachables ?
before starting analytical method valodation what you checking? and how giving preference to start validation?
calibrtion procedue of LC-MS
If we have 5 strength which is not dose proportinate and excipients also diffrent in each strength then how we can proceed for Force degradation? and excipient are same but not dose propotinate the how FD?
Principle of single pan analytical balance
inhouse product is in capsule form in combination and RLD is in tablet form then can we proceed for multimedia CDP? in inhouse capsule product disso is paddle with sinker in release media is there then RLD product in tablet form then with same as paddle with sinker we can proceed n.a.?
is it necessary to do HPLC calibration at wavelength 315nm if we are doing analysis at this wavelangth
which are the sizes of capsules?
In GC calibration,what is the procedure to calibrate the TCD (thermal counductivity detector)suggest ?
In rs method development when we are going area normalization method to dilute standard method?
Which type of column should i use to check the purity of high molecular weight protein using HPLC reverse phase column chromatography? Hi everyone. I wanna to check the purity of high molecular weight protein (collagen) with MW of ~130 kDa using a HPLC. I know C18
What is control room temperature and which guide line says?
What is the diffrence in japan mkt requirement in analytical method validation over US?
give clarity of linearity and range in method validation
effect of pore size, pore volume, partical size, column length, carbon load on retention time? what is carbon load? what is the use?