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What is the difference between IGA and IGM of
immunoglobulins?
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Answer Posted / turyagumanawe john
IgA a dimer when found in secretions and monomer in
serum,It is divalent,SIgA has a secretory piece and a J
chain;it is present in secondary immune response than
IgM.It is 2nd most common Ig i serum,seldom fixes
compliment and is the major Ig in secretions.
IgM is a pentamer but can sometimes exist as a monomer,has
an extra domain of CH4;3RD most common serum Ig,dominates
primary immune response,fixers compliment ,has a valency of
10 and activets B cellin the T-depentent and T-independent
pathway.
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