what is the relative response factor in related substances?
is it necessary to calculate?
- 9 Answers
- 34821 Views
- Elysium, Sun Pharma, I also Faced
- E-Mail Answers
Answer Posted / subhashini
Definition of relative response factor :
A measure of the relative response of the instrument
detector to an analyte compared to an internal or external
standard. Relative Response Factors are determined by the
analysis of standards and are used to calculate the
concentrations of analytes in samples. The RRF can be
calculated using the following equation:
RRF = (Ac x Cis)/(Ais x Cc)
where,
RRF = Relative response factor
Ac = Area of the target analyte
Ais = Area of the corresponding internal standard
Cis = Concentration of the corresponding internal standard
Cc = Concentration of the target analyte
| Is This Answer Correct ? | 29 Yes | 1 No |
Post New Answer View All Answers
What is Calibration Curve?
What is blank?
what are the GLP activities to be followed for Oncology products
why we are performing linearity test for assay and rs?
What are the factors on which the gas sterilization depends on?
Explain hydrophobia?
what do you think is the most challenging aspect of a pharmaseutical representative?
Why pipetting training is crucial for clinical technician?
What are the steps you can take to avoid imbalance in centrifuge?
Why GLP is followed in the lab?
What is supernatant?
IN OOS SAMPLING ERROR HOW CAN WE ADDRESS , OR HOW CAN WE EXPLAIN AUDITOR ABOUT SAMPLING ERROR
i am doing a dissolution test then what is the rsd criteria for the six results obtained after calculation?is there any reference in any guideline for rsd criteria?
explain the selection criteria of a control
what is the range of ftir as per usfda?
