Answer Posted / mr. bujji reddy kanchi

the difference between these two columns is packing only
C18- octa decyl chain linked to silica.
c8- only octyl chain linked to silica.


C18 is widely used, the polymeric C18 format incorporates a
tri-functional silylation procedure whereby the octadecyl
group is bonded to 2 or 3 silica atoms on the silica gel
backbone. This increased silylation results in far greater
column stability particularly in acidic mobile phase
conditions. Stereo recognition capability is also greater
than that of the monofunctional silylation type of C18.

How would you decide dissolution medium for NCE compound of class I drug

2191

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Which is the highly polar and highly non polar column in HPLC?

2237

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on saturation solubility study data how we can find out the bcs class of drug?

826

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why we should take dst factor for below 1%moisture samples

2611

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in which situation require to use paddle and basket?

669

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what is partion and column chromatography

2297

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how much mass should be there in volumetric flask while in preparation of sample for assay? 

2510

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can i use hplc detector to uplc and why?

2236

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how to develop the icp ms method? Application of icp ms?

745

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How we can identify process related and degradation impurity in single method with short period?

757

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what is mean by peak intigrity?

860

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Which parameter require to do for analytical method equivalency?

728

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why glutent are detected in the rice cereal baby food product even manufacturer claimed that they are using rice and milk only?we have using ELISA to do the test,and rice supposed not containing any glutent,rite?We already repeat the test so many times and it still detected.just wondering where the glutent came from?

2704

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if identification threshold crosses the limits then what next step?

797

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What should be the level/ Percentage of Arsenic in Arsenic free zinc.

2177

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