Answer Posted / shravan kumarm

Initially we have to prepare a normal solution and to
standardise that solution against aknown fresh normal
solution.After that in particular time intervals for
examples o th day ,7 th day ,15th day and 30th day we have
to restandardise that initial normal solution against a
fresh known noramal solution each time .up to which
interval the normality of initial solution will not differ
by more than +/-0.002,that interval day we can fix it as
validityperod.In this mean time we have to consider the
physical apperaence of the solution also in to cosideration.

calibrtion procedue of LC-MS

2702

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what is partion and column chromatography

2374

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WHY pKa value is more important than pH value of the mobile phase in HPLC?

1755

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acceptance criteria for lod & loq by standard deviation of response and slope??

2582

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pharma industries oriented

2225

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What is shaking level in GC?

783

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How to decide assay range for non pharmacopeial API analysis by HPLC? Could you give me any reference for same e.g Guidelines or Paper publications?

3345

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In the HPLC Calibration done wavelength accuracy done between 200nm-280nm .but not done remaining 300-400nm not done ?

912

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If we do accuracy at same concentration at which linearity planned,what is the need to do linearity separately?

2291

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How require to develop GC method? how to select diluent, GAS, column selection and other chromatographic conditions?

720

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if rsd failed then what require to do?

820

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If combination product how require to identify which imp is of which api?

834

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what is difference in ods I ods II is this is realy from sorbent / packing characteristics or from other means

1960

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What is the principle of HPLC, GC, LCMS, GCMS,LC QQQ, GC QQQ, LC Q TOF and GC Q TOF. What are the applications and Specificity?

8855

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if you get peak in blank then what require to do?

963

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