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What should be the precision for HPLC during technology
transfer?
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Answer Posted / basha
6 times of system suitability will be considered as system
precission.6 times of different assaying is method
precission
| Is This Answer Correct ? | 2 Yes | 3 No |
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2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.
