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which solvent is highest poler
acetonitrile
dimethyl formamide
methanole
tetrahydrofurane
buffer solution
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What is the formula for relative diffrence for standard solution in solution stability in validation?
what is definition of validation? which components are followed give detail?
Why we used in n-butyl acetate water content terminology while in ethyl acetate we used moisture content terminology?
In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.
why require the ph, buffer during hplc mobile phase?
If inhouse hplc related substance method is completly diffrent from Usp for finished proďuct with diffrent impurities then how require to prove method equivalecy?
What is diffrence between extractable volume and deliverable volume? Answer pls
how we can identify the impurity is coming below loq at transfering site?
Ph meter can show more than 14 ph reading? Why ph range in between 1 to 14 only?
What is delay volume?
why sre you used Potassium hydrogen phthalate in standarisation of 1N NaOH and 0.1 N Perchloric Acid?
What is the diffrence in japan mkt requirement in analytical method validation over US?
I have compare C2H2-air and C2H2-N2O flame AAS on determination calcium. Both use same range of std to plot calibration curve. (2-6ppm) When i measure the sample with phosphate, KCl and LaCl, C2H2-N2O flame give false positive result, around 0.5ppm. When i measure the sample with phosphste, KCl and EDTA. C2H2-N2O flame also give 0.5ppm false positive. But both above mentioned sample would not give false positive when measured by C2H2-air flame. What is the reason?
If we have 5 strength which is not dose proportinate and excipients also diffrent in each strength then how we can proceed for Force degradation? and excipient are same but not dose propotinate the how FD?
in stress study if your api not soluble in hcl naoh h2o2 then what require to do?
