How the NUCLEOSIDE ANALOGUES ARE USED AS DRUGS?
Answer Posted / spandana
Nucleoside analogues 3'azidodeoxythymidine and
2',3'-dideoxycytidine used for the treatment of AIDS.when it
is given to aids patients ,azt and ddcare converted into
triphosphate forms which compete with dttp and dctp as
substrates for dna synthesis.as dna synthesising enzymes of
hiv are sensitive to azt and ddc inhibition these
nucleoside analogues acts as drugs for hiv patients.
| Is This Answer Correct ? | 6 Yes | 0 No |
Post New Answer View All Answers
Aldehydes and ketones characteristically undergo which reactions?
How the production of rna called?
What are respectively some remarkable functions of immunoglobulin?
Define kararch effect?
In the geometrical isomerism, if the similar groups are present on opposite side is called as?
What are respectively some remarkable functions of insulin?
What is lattice energy?
Since pepsin is a gastric enzyme does it, has acid or basic optimum ph? What happen to pepsin when it passes to the duodenum?
ano po ba ang bermuda triangle? ano po ang nandito? meron po bang mga naitala na aksidente sa gawing ito? ano po ang scientific question nito?
Who proposed law of mass action? What does it states?
What causes the elasticity of corneal layer of skin?
What is the molecular formula, structure, and bond angle of phosphorous?
What are pentoses?
What happen to a denaturated enzyme regarding its functionality? How that result can be explained with the help of the lock and key model?
How do you define the molecularity of a reaction?