What is the main idea of maximum parsimony in phylogenetic
tree construction? What are the drawbacks?
Answer Posted / rajalingam
The Maximum Parsimony (MP) problem aims at reconstructing a
phylogenetic tree from DNA sequences while minimizing the
number of genetic transformations. To solve this NP-
complete problem, heuristic methods have been developed,
often based on local search. In this paper, we focus on the
influence of the neighborhood relations
| Is This Answer Correct ? | 3 Yes | 0 No |
Post New Answer View All Answers
Have the proteins of a family generally acquired distinctive properties within each of these three kingdoms for ancient families that arose before bacteria, archaea and eukaryotes diverged?
What is the secondary structure of intron ?
What is the difference in terms of connectivity between a scale free network and random network?
Did bacteria, archaea, and eukaryotes exchange transporter genes appreciably during the past two billion years?
What are the main differences between parsimony,distance and likelihood-based algorithms?
How to predict the function of a gene (product)?
What is computational biology?
How to run DOCK 6 using cygwin?
A certain radioactive element A, has a half life = t seconds. In (t/2) seconds the fraction of the initial quantity of the element so far decayed is nearly how much?
How can we find the direction of an nucleotide substitution, for example; C to T or T to C?
Bootstrap analysis evaluates evolutionary trees by sampling columns from the original alignment with replacement (multiplying or removing some of them) and computing a proportion of times that a particular branch appears in the resulting trees. What is the main idea behind this approach?
How do you customize database for blast?
Are all members of transporter families confined to a particular organelle or to the plasma membrane, or are some family members found throughout cellular compartments in eukaryotes?
Suppose the Blast search returned 100 hits. Of these, 17 were false positives and we knew that there were 165 sequences in the database which should have returned a hit with our sequence. How many false negatives were there, and what is the sensitivity and selectivity of Blast in this instance?
NLO : RPS : : ? : ZXA