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Un-Answered Questions { Biological Sciences }

What factors can change the pKa value of an amino acid residue, and in which direction?

2526


How does hplc differ from normal column chromatography, and what are its advantages?

2121


How are free energy changes related to enthalpy changes and entropy changes?

1959


Why are right-handed helices more stable than left-handed helices?

2537


How are reaction rates dependent upon free energy changes?

2304


Why are free cysteines treated with iodoacetate prior to protein sequencing?

2334


How are free energy, equilibrium and spontaneity related to each other?

2139


Where do hydrophobic and hydrophilic residues usually end up after protein folding?

2182


What are the structures of the products of this reaction, and how are they identified?

1994


How does a random coil differ from an irregularly structured region?

2164


What are hydrophobicity scales, and how are they used?

1839


How are coupled reactions used in biochemistry?

2301


What type of column is generally used to separate amino acids from each other?

2063


Why is the t-butyloxycarbonyl protecting group such a good choice for amino acid synthesis?

2090


How much empty space is found in globular proteins?

2031