What factors can change the pKa value of an amino acid residue, and in which direction?

2607

---

How does hplc differ from normal column chromatography, and what are its advantages?

2184

---

How are free energy changes related to enthalpy changes and entropy changes?

2004

---

Why are right-handed helices more stable than left-handed helices?

2586

---

How are reaction rates dependent upon free energy changes?

2337

---

Why are free cysteines treated with iodoacetate prior to protein sequencing?

2387

---

How are free energy, equilibrium and spontaneity related to each other?

2171

---

Where do hydrophobic and hydrophilic residues usually end up after protein folding?

2216

---

What are the structures of the products of this reaction, and how are they identified?

2046

---

How does a random coil differ from an irregularly structured region?

2208

---

What are hydrophobicity scales, and how are they used?

1867

---

How are coupled reactions used in biochemistry?

2352

---

What type of column is generally used to separate amino acids from each other?

2110

---

Why is the t-butyloxycarbonyl protecting group such a good choice for amino acid synthesis?

2143

---

How much empty space is found in globular proteins?

2077

---