A blastomere was removed from an 8-cell human embryo, and
its beta-globin gene was amplified by PCR. The beta-globin
DNA was treated with an enzyme that cuts on either side of
and within the normal allele (producing a small fragment),
but not within the sickle cell allele (producing a large
fragment). Electrophoresis of the treated DNA from the
blastomere demonstrated the presence of both a large and
small fragment derived from the beta-globin genes. How
should you interpret this test?
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A blastomere was removed from an 8-cell human embryo, and its beta-globin gene was amplified by PCR. The beta-globin DNA was treated with an enzyme that cuts on either side of and within the normal allele (producing a small fragment), but not within the sickle cell allele (producing a large fragment). Electrophoresis of the treated DNA from the blastomere demonstrated the presence of both a large and small fragment derived from the beta-globin genes. How should you interpret this test?
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