what is chloramphenicol solubility ?
- 1 Answers
- 9090 Views
- I also Faced
- E-Mail Answers
Answer / aditi
In purified water the solubility of chloramphenicol is only
0.25%.
Several approaches such as pH adjustment, complexation ,
micellar solubilization , cosolvency were successfully
employed to enhance the solubility. The present market and
official preparations contain chloramphenicol in water, the
pH adjusted with boric acid/borax buffer to enhance to the
required solubility (5 mg/ml). Similarly, when the pH is
raised to 8.6, its solubility reaches to 1%. However, the
stability and activity are much reduced.
Solubility of non-ionizable substances can be enhanced by
the addition of non polar solvents and when mixture of
solvents such as PEG 300 are used along with water, the
technique is generally termed as cosolvency techinque.
| Is This Answer Correct ? | 9 Yes | 2 No |
What is babesiosis?
Why are the bacilli arranged at angles to each other?
what is Acanthamoeba infection?
What is the simple method for isolating parasite DNA from clinical samples?
Give an account on Enterotoxin ?
Give an account of Organic sulphur oxidizing bacteria ?
Describe the Stabilisation of Barium sulfate precipitate in McF' scale ?
Explain the importance of pseudomonas?
Explain about Protein Modification (S-thiolation)?
i have rejected once for the reason that why am i not applied for master. as i am already post graduate and i have got i20 for the degree course which is very helpful in my professional career. what should be the best ans to resolve it.
where is black sea located
Give an account of antibodies against pET30c fusion protein ?
Micro Biology 
