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How will you differentiate alleles of a gene in the double strand of DNA?
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A certain man has the genotype AaBb; genes A and B are on one chromosome and a and b are on its homologue. List the gametes that could be formed with crossing over and with no crossing over
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A blastomere was removed from an 8-cell human embryo, and its beta-globin gene was amplified by PCR. The beta-globin DNA was treated with an enzyme that cuts on either side of and within the normal allele (producing a small fragment), but not within the sickle cell allele (producing a large fragment). Electrophoresis of the treated DNA from the blastomere demonstrated the presence of both a large and small fragment derived from the beta-globin genes. How should you interpret this test?
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