How the malaria parasite evades detection by the human
immune system?
- 1 Answers
- 4453 Views
- I also Faced
- E-Mail Answers
Answer / dr.suhasini bhatnagar
In malaria, Plasmodium falciparum uses various red blood
cell invasion mechanisms to evade the human immune response,
which eventually causes the disease. Antibodies that prevent
P. falciparum from invading red blood cells (erythrocytes)
are believed to be important components of immunity against
malaria. The malaria parasite interferes with the function
of dendritic cells, stopping them from maturing and from
'presenting' antigen to naive T cells. The parasite does not
interfere with the human cells directly. Instead, it
produces proteins that are then found on the surface of the
red blood cell it is hiding within. These proteins bind to a
molecule called CD36, found on the surface of the dendritic
cells (and on the surface of other immune cells).This
binding causes the dendritic cells to become inhibited,
stopping them producing sufficient proteins of their own
required to make prolonged contact with naive T cells. The T
cells become unresponsive and so a successful immune
response is thwarted.
| Is This Answer Correct ? | 3 Yes | 0 No |
what is global warming?
what is unique about the life cycle of the dog tapeworm?
How to produce clear agar ?
How do you find the D and F value for Biological indicator, in the autoclave?
What is the ph range of most bacteria and most fungai.
what are the Advantages of Protoplast fusion ?
How to keep stock for fungal strain?
Which is the more important step in gram stain?
What are the applications of gram staining?
Describe the direct and indirect methods for measuring bacterial population growth?
How to identify a new bacteria species?
What is the temperature and time employed to sterilize the articles in hot air oven?
Micro Biology 
