What is Pharmacogenetics?
Answer / guest
Pharmacogenetics is a subset of pharmacogenomics which uses
genomic/bioinformatic methods to identify genomic
correlates, for example SNPs (Single Nucleotide
Polymorphisms), characteristic of particular patient
response profiles and use those markers to inform the
administration and development of therapies. Strikingly,
such approaches have been used to "resurrect" drugs thought
previously to be ineffective, but subsequently found to
work with in subset of patients. They can also be used for
optimizing the doses of chemotherapy for particular
patients.
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