Answer / dm

prepare the standard solution as per impurity level.

Answer / yantesh varshney

If Impurity peak have very low response in this case we prepare diluted standard as per criteria generally at 1 % level to check and compare the impurity with in limit .

Answer / sunil

Actually it is based on the impurity level if any impurity does not meet his LOQ level at that concentration w.r.t the API in that case we need to increase concentration of the API and if the peak is normal no need to prepare diluted std but if peak goes saturation in that case need to inject diluted std at SHI level

Shall i use a same hplc column for two different products.?

3 Answers  

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For LOD and LOQ determination which method is accurate? (slopemethod or s/n ratio method)

4 Answers   Reddy Labs,

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why we are taking 85 ml of concentrated HCl to prepare 1N Solution

4 Answers   SG Phyto Pharma,

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which lights using during force degradation?

1 Answers  

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Difference Between End Cap HPLC Column and Non End Cap Column

2 Answers  

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Why we use buffers Acetate for pH 4.5 & phosphate for 6.8 and not vice-versa?

1 Answers   Zydus Cadila,

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How to calculate mass balance in RS after degradation

1 Answers   Reddy Labs,

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same sample on two preapration gives differnt result during hplc analysis

3 Answers  

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What is difference between known and unknown impurities

1 Answers   Sun Pharma,

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1 why polyesterene film used for ftir calibration ? 2 why k2cr2o7 is used for control of abs in uv ? 3 why holmium oxide used for control of wavelength in uv

3 Answers  

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In case of dissolution test, if there is variation within 6 individual units however the batch is complying as per S1 criteria, is it necessary to do investigation for the same? What should be the criteria for such variation?

2 Answers  

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Why the ph limit (1_14) Is used?

3 Answers   Cipla,

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