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What is difference between Chromatographic purity and
Related substances analysis?
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Answer / arumugam
chromatographic purity is %area normalization is nothing
but Impurity area/Major compound area, applicable for all
known and unknown impurities.
But Related substances is quantification of all impurities
nothing but the impurities are quantified by know
concentration of standard solution.
Impurity (%w/w)= Imp area* Std. Dilution*Potency of Std*RRF
------------------------
Std Area* sample Dilution
RRF= Relative Response factor
| Is This Answer Correct ? | 27 Yes | 1 No |
Answer / gayathri
Chromatographic purity is a qualitative analysis and Related substances is a quantitative analysis
| Is This Answer Correct ? | 6 Yes | 5 No |
Answer / amol
chrom purtiy is used when all the impurity is known and in
related substances used for both known as well as unknown
impurtiy
| Is This Answer Correct ? | 8 Yes | 21 No |
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