Answer / tushar

First check it is volatile or non volatile because HPLC is
for volatile or non volatile component and GC is for only
volatile component.After for HPLC check solubility of
component then v can use check UV , PDA , Refractive index
detecter.GC for FID,TCD,ECD detecter etc.

Answer / aruna k

First cheeck the volatile nature & thermal stability of
compound,if it is highly volatile, thermal stable go for
gc,if it is not(i.e,non volatile&thermally unstable) we can
prefer hplc.

Answer / viss u

first check the UV spectrum of the compound if spectrum is
available go for hplc, if not that is UV inactive so start
method with GC.

Answer / gopal chaudhari

if compound is volatile analytical method will by GC.
and if compound nonvolatile means it decomposes on heating
for this will use hplc.

Answer / chandu

to inject the sample

why the same column give different retention time in hplc?

7 Answers  

In gas chromatographic analysis sometimes we use headspace, why it is required instead of manually injection?

1 Answers  

Which buffer is used for LC/MS mobile phase & at What Conc.

3 Answers  

What is Threshold in hplc?

2 Answers   Hetero,

Do you have experience with organic extractions or tissue digestions?

1 Answers   GVK Biosciences,

why we use only sucrose in the calibration of polarimeter?

7 Answers   Kilitch,

on what basis SOP's can be changed? IF mobile phase ratio is 70:30 to how much % can we change the ratio in HPLC process

7 Answers   Cipla, Ranbaxy,

Difference between related substances & impurities

2 Answers   Biocon,

WHICH PRESSURE IS HIGH EITHER INJECTOR OR DETECTOR IN GAS CHROMATOGRAPHY

4 Answers   Avon Organics, Dr Reddys, Reddy Labs,

what is different when impergnated silica plates are used in separation of azo dyes using column chromatography?

0 Answers  

why cone formation during dissolution?

0 Answers  

what is polarity and how to calculate

2 Answers   Reddy Labs,