What is the limit for friability of tablets?
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Answer Posted / s.k.afridi
Friability test is used to determine the physical strength
or tablet breaking force for compressed, uncoated tablets.
Tablet Friability Apparatus is used for the test. Remove
any loose dust from the tablets and accurately weigh 10
tablets or weight of the sample NLT 7 gm for small tablets. They are placed in the drum which rotates at 25±1
rpm. Rotate the drum 100 times, and remove the tablets.
The sample fails the test, if any of the 10 tablets
cracked, cleaved, or broken is present. If the weight loss
is more than 1.0%, the test is repeated for twice and the
mean of three tests is calculated. The mean not more than
1.0% is considered acceptable.
Please note that for Effervescent tablets and chewable
tablets the friability limits may differ.
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