What is discriminating media? How can u justify/select that
which media (pH etc...)is suitable for your dissolution study
of your compound?

Answer Posted / pramod

Discriminating media is a media which shows variation in results with different formulations.I.e.Chang in excipients,excipients composition etc

Is This Answer Correct ?    11 Yes 0 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

which one is better separation in high pressure liquide chromatogram orlowpressure chromato gram in hplc

1732


How to do regeneration of Metacarb Pb plus column?

2083


What is control room temperature and which guide line says?

1162


what is the extinction coefficient for Indomethacin or at 319nm wave length.

3525


What if impurity area in control sample coming more as compared to LOQ level of impurity ?

1152






if your product is soluble in 0.1n hcl and water then which you choose as media from these 2 media?

280


what is the acceptance criteria for enteric coated tablets in 0.1n hcl validation in each parameter?

351


why multimedia dissolution require to do?

312


Why are use silicon oil mr?

751


How we can identify process related and degradation impurity in single method with short period?

340


What is importance of pH in the Heavy metal test and How it effect on the test results?

1760


what is partion and column chromatography

1820


What is diffrence between extractable volume and deliverable volume? Answer pls

3938


in which situation require to take incident in validation?

777


if content uniformity passing but dissolution varrying then what is next step?

394