Answer / krishnamurthy

Purity indicates existence of of required compound rest of
other components(impurities) in a sample matrix.

Potency indicates the strength of required compound rest
of other components(impurities,MC,ROI, OVI,etc) in a sample
matrix. This potency correction is useful for the weight
correction. This gives the exat weight which we taken.

Answer / sai

Purity means- it explains how pure our analyte is in the given mixture. It is not related to the how much our analyte is in the given mixture. i.e  percentage of our analyte without impurities in HPLC (i.e known or unknown)  

Potency means-  it is measurement of our analyte  how potent it is.  i.e  purity of our analyte without all possible impurities like chromatographic impurities (HPLC, GC-Residual solvents, TLC), Heavy metals etc..

Answer / hardik patel

diff.b/w validation & calibration

I want analyze my compound at 325 nm so which standard shall i use to calibrate my HPLC system? How i can assure my hplc detector is suitable or not?

3 Answers   AMRI,

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In chromatograpbic purity 90% is there, in assay 70% is there. How will you prove remaining 30%.

3 Answers   Dr Reddys,

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What is the composition of K.F

6 Answers   IPQA,

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if the flow rate is increases then any changes in retention time in hplc

1 Answers  

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How to study genotoxicity of impurities in API?

2 Answers   NCL,

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What is the difference between high pressure gradient and low pressure gradient in hplc?

1 Answers   Cipla,

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The boiling point of 1,3 butadiene is -4.4 DC & the boiling point of Pentane is 36.1 DC. Then how come Pentane elute before 1,3 BD in GC analysis?

1 Answers  

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how pyridine can be analysed other than GC?

1 Answers  

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What will be the effect on HPLC analysis result if three mobile phases given separately through three valves and same proportion mixed together and given by one valve?

1 Answers   LOIL,

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Chromatographic Purity is a Qualitative analysis

2 Answers   Shasun Chemicals,

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what should be the precision during technology transfer?

3 Answers   Glenmark,

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Why we select scan range from higer wavelength to lower wavelength in uv visible spectroscopy and ftir spectroscopy ? .

0 Answers  

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